Therapeutic Simvastatin - Statins.Names of preparations - Aterostat, Vasilip, Zovatin, Zocor, Zorstat, Levomir, SimvaGEKSAL, Simvakard, Simvakol, Simvalimit, Simvastol, Simvor, Simgal, Simla, Simplakor.
Simvastatin - instructions for use
Doses and frequency of use of simvastatin In the early course of a single dose of 5-10 mg / day, if necessary, to 40 mg per day depending on cholesterol and lipoproteins in the blood..In ischemic heart disease the initial dose of 20 mg / day.once
Valid Simvastatin 2-4 weeks
Duration Simvastatin effect is maintained throughout the treatment period.
If simvastatin skipped Take the missed dose as soon as you remember about it.Take the next dose at the usual time and go back to the usual pattern.
Stopping Simvastatin decision on the termination of the medication should be taken after consulting a doctor.As soon as you stop taking simvastatin, cholesterol, may return to the original higher value.
simvastatin special instructions essential elements of the fight against high cholesterol are diet, weight loss, regular moderate exercise, and the rejection of certain drugs.
simvastatin to reduce cholesterol levels.The drug is also used to reduce the risk of stroke or transient ischemic attacks ( "minor strokes") in patients with elevated cholesterol and coronary heart disease.Usually it is prescribed after the priority actions, including changes in diet, weight loss and increased physical activity, do not lead to a reduction in total cholesterol and low density lipoprotein (LDL) in the blood.
Medicinal properties Simvastatin Simvastatin
blocks the action of one of the enzymes needed to produce cholesterol, and thereby prevents its formation.By lowering the amount of cholesterol in the liver cells, the process of forming simvastatin intensifies the LDL receptors resulting in decreased total and LDL cholesterol levels in the blood.Additionally, simvastatin reduces the number of triglycerides and increases high-density lipoprotein (so-called "good" cholesterol).
Simvastatin Side effects and contraindications
Simvastatin - contra Hypersensitivity, severe liver dysfunction, severe renal failure, pregnancy, lactation, children's age.
Side Effects Simvastatin temperature, chest pain, unusual or unexplained muscle aches and soreness.Immediately call a doctor.Side effects observed in only 1-2% of patients.Some of these actions include constipation or diarrhea, dizziness, flatulence, or bloating, heartburn, nausea, skin rash, stomach pain, increased liver enzymes.Rarely is insomnia
Forms release simvastatin
Precautions for the use of simvastatin
Older than 60 years Special problems are expected
machines Driving and working with mechanisms Applicationsimvastatin should not interfere with these activities.
Alcohol drug increases the toxic effect of alcohol on the liver.
Overdose simvastatin overdose is unlikely.Instructions for urgent action is required
Interactions Consult your doctor if you are taking cyclosporine, gemfibrozil, niacin, antibiotics (especially erythromycin) or medicines for fungal infections.All of these drugs when administered with simvastatin increases the risk of myositis (inflammation of muscle) and can cause renal failure.